Key left winger and Welsh International Gareth Roberts has a shoulder injury, and has been missing since Tranmere's away trip to Brentford back in April.
Whilst set-piece taker and right back Ryan Taylor who was Right Back in the League One team of the year is also injured with a bruised ankle sustained at Port Vale forcing him to sit out the MK Dons game.
However, both are expected to be fit for the play-offs but it's more 75-25 than 100-0.
Whereas, Danny Harrison, Tranmere's young and ever improving Central Midfielder is a doubt for the first game in the play-offs away to Hartlepool. Harrison picked up a leg injury at the National Hockey Stadium against the MK Dons and is very doubtful for the trip up to the North East. This will be a big loss for Tranmere.