Parry is a qualified physiotherapist and worked with Tranmere Rovers in that capacity since the early nineties before succeeding John Barnes in the managerial position at Tranmere.

Parry should not be confused with the other Les Parry who played for Tranmere in the 1970s and early 1980s, making over 250 league appearances for the club.

Rovers sacked manager John Barnes and his assistant, Jason McAteer, after a run of just two league wins from 11 matches on 9 October 2009. As a result, Parry was placed in temporary charge, to be assisted by reserve boss Shaun Garnett. His first match was a 0–1 home loss to Stockport.

On 16 December, he was appointed manager until the end of the season after an encouraging five wins and three draws as caretaker boss.

Parry successfully kept Tranmere in League One, securing the team's place for next season with a vital victory away at Stockport on the final day of the 2009-10 season.

Parry's first job was in a Liverpool shipyard, he started as part-time physiotherapist at Tranmere before being appointed full-time by Johnny King in 1993.

He has completed a PhD in "Sports injuries in professional soccer and the effects of detraining" at Liverpool John Moores University.

Parry released a single named "I'm Les The White Legs Parry" which changed words from "The Red-Nose Reindeer" in 2006. It sold 2,000 copies to raise money for charity.